National Football League
Injury report for San Francisco 49ers at Seattle Seahawks (National Football League, Lumen Field (Seattle)): San Francisco 49ers have 4 out and 1 doubtful; Seattle Seahawks have 4 out and 1 doubtful.
San Francisco 49ers
- Nick BosaDEOut
Knee, Calf — Calf injury, out multiple weeks (knee also managed)
- Kyle JuszczykFBOut
Knee
- Marques SigleSOut
Ankle
- James Thompson Jr.DTOut
Ankle
- Upton StoutCBQuestionable
Shoulder
QB Brock Purdy starts. DL CJ West on IR; edge Alfred Collins (torn patellar tendon) out for season. DE Mykel Williams activated off PUP and removed from injury report. LB Matt Judon released.
Seattle Seahawks
- Zach CharbonnetRBOut
Knee
- Julian NealCBInjured list
Hamstring — Placed on IR
- Chazz SurrattLBOut
Calf
- George HolaniRBQuestionable
Ribs, Knee
- Irvin CharlesWROut
Knee — Downgraded to out on Saturday
QB Sam Darnold starts. CB Trevon Diggs signed to active roster.